CLINICAL PHARMACOLOGY IN PEDIATRIC ALLERGOLOGY AND IMMUNOLOGY. МODERN OUTLOOKS OF POSSIBILITY OF APPLICATION THE CONCEPT OF A SINGLE INHALER FOR THE THERAPY OF BRONCHIAL ASTHMA. FEATURES OF USE IN ADOLESCENTS

P. 34-40

V.V. Syrov

Scientific and clinical advisory center of an allergology and immunology, Moscow, Russia

Bronchial asthma is one of the most common non-infectious diseases among different age groups. The main goal of therapy is considered to be achieving complete control over the symptoms of the disease. Patients in adolescence should take into account the existing psycho-emotional and social characteristics that may hinder the achievement of optimal results of therapy. It should be borne in mind that for this age is characterized by a low adherence to therapy, this is due, as a rule, to poor cooperation of the adolescent with parents and medical workers. The basis of therapy for asthma of a moderate persistent current is the basic therapy, which is mainly performed by a combination of inhaled glucocorticosteroids with long acting β2-agonists. In addition to basic therapy, as short-acting drugs for the relief of asthma symptoms, short-acting β2-agonists are used. Currently, adult patients have adopted the concept of using a single inhaler, which is used for both basic therapy and for relief of asthma symptoms. The effectiveness of the tactics of using a single inhaler, including in adolescence, has been proven by a number of clinical studies. However, more research is needed, since the data for using this tactic in adolescents is not enough.

Keywords: bronchial asthma, SiT-therapy, SMART-therapy, budesonide/formoterol.

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