ORIGINAL ARTICLE. THE IMPACT OF ATOPIC SENSITIZATION ON RECURRENT LARYNGOTRACHEITIS IN CHILDREN

P. 33-40

A.G. Chuvirova, M.N. Yartsev

 

Institute of Immunology, Moscow, Russia

 

The object of investigation. Generalization of results оf an allergological eхamination of children with recurrent laringotracheitis (RLT), monitoring during three years and researching of an association between RLT and atopic sensitization.

Materials and methods. Eighty children (52 boys and 28 girls) 3-15 years old with RLT were investigated (64 children 3-7 years old and 16 children 7,1-15 years old). Allergodiagnostic included: patch-tests, IgE.

Results. More than a half (47/58,75%) of investigated children with RLT had allergic deseases: seasonal allergic rhinitis, allergic rhinitis, atopic dermatitis, bronchial asthma. Essentially a half of relatives of mother’s or on father’s side of the family had allergic deseases. IgE levels varied from 50 to 2000 IU/ml, a polysensitization was noted (household, pollen allergens). Sensitization wasn’t identified in 33 (41,25%) children. Seasonal allergic rhinitis was diagnosed in 20 (25%) children, atopic dermatitis — in 21 (26,2%), allergic rhinitis — in 6 (7,5%), the combination of seasonal allergic rhinitis and atopic dermatitis — in 6 (7,5%), bronchial asthma — in 20 (25%).

Conclusion. Manifestations of allergic deseases were diagnosed in more than a half of children (58,75%) with RLT. The predisposing factor is a hereditary load in atopic diseases: a part of relatives (48,5%) of mother’s or on father’s side had allergic diseases. A three-year case-monitoring showed than a quarter of children (20, 25%) had RLT without laryngeal stenosis, a half of children (40, 50%) had laryngotracheobronchitis and a quarter of children (20, 25%) had bronchial asthma. Children with RLT and hereditary load in atopic diseases need for an allergologist medical supervision.

 

Keywords: reccurent laryngotracheitis, allergic diagnosis, atopic sensitization, laryngotracheobronchitis, bronchial asthma.

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