D.Sh. Macharadze1, I.A. Larkova2, V.A. Revjakina2, V.I. Peshkin1, I.S. Sadikov3
1 Рeoples Friendship University of Russia (RUDN University), SM-clinic, Moscow, Russia
2 Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia
3 Clinical Hospital № 17, Moscow, Russia
Eosinophilic esophagitis (EoE) belongs to the group of gastrointestinal eosinophilic diseases, which is rarely diagnosed in real clinical practice by Russian doctors, especially in children. Initially, EoE was considered a predominantly childhood disease. EoE should be suspected in patients with allergic diseases (most often male) and in combination with dysphagia and/or other complaints from the gastrointestinal tract. Over time and, especially, with inadequate therapy, EoE is accompanied by the formation of strictures and fibrous changes in the esophageal tissue. EoE is a clinical and morphological diagnosis, which requires a biopsy of the esophageal mucosa, which reveals an increase in the level of eosinophils (≥15 in sight, x 400) in the esophageal tissue (without
other alternative causes of eosinophilia).
Keywords: clinicalcase, eosinophilic esophagitis, diagnosis,children, treatment.