ATOPIC DERMATITIS IN CHILDREN AS A MULTIFACTORIAL DISEASE, CAUSES AND TREATMENT CHARACTERISTICS P. 8-14
R.A. Mingaliev, A.V. Kudryavtseva
State budgetary educational institution of higher professional education «I.M. Sechenov First Moscow State Medical University», Russian Ministry of Health, Moscow, Russian
Atopic dermatitis is a common inflammatory skin condition in children. It is a chronic disease with periods of remission and flare-ups. Atopic dermatitis influences the quality of life of pediatric patients and their families. Topical corticosteroids are still the mainstay of treatment in acute phase as well as the standard AD therapy. Topical calcineurin inhibitors are not indicated for use in patients younger than two years or in those who are immunosuppressed, and should be regarded as second-line therapy in other patients. Rarely, systemic agents (e.g., cyclosporine A, oral corticosteroids) may be considered in severe atopic dermatitis cases when external treatment has no effects. Biological therapy – one of the modern treatment options are likely coming to replace the immunosuppressive and hormonal treatment of atopic dermatitis in the progressive course of the disease.
Keywords: atopic dermatitis, heavy current, children, treatment, glucocorticosteroids, cyclosporine A, external therapy, antihistaminic medicines, psychosomatic diseases.